Charlie Green, a rising black monologist of the early 1980s wants to soon become a professional writer and actor on the tv set. Unfortunately, there is one roadblock to his rise in fame and it's his addiction to the hallucinogenic drug PCP, also know as Phencyclidine.
Through Charlie's addiction, he mistakenly thinks that his monologues will benefit in quality because of the drug and he will also make it to the top with his newly acquired "creativity." As every one of his decisions begin to take their toll on his mind and body, his addiction also begins to harmonize with his life. Now, the woman that he loves becomes increasingly affected by his choices on where he takes his life; or where the drug will. Karmony meaning Karma and Harmony.